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Zụrụ OXYCODONE 30MG X 100 TABLETS ONLINE | MUSHROOMIFI

Name: OXYCODONE 30MG X 100 TABLETS - Zụta ero ime Anwansi n'ịntanetị |MushroomiFi
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Oxycodone a na-eji ọgwụ eme ihe kemgbe 1917. Zụrụ Oxycodone Oxycontin 30mg online na Australia
A na-enye mmadụ ya n'ime intravenous (iv),
intramuscularly (im),
intranasally (n'ime),
subcutaneous (sc),
n'ezie,
epidural,
na ọnụ na-eji ngwọta mwepụta ngwa ngwa, na mbadamba mbadamba na-achịkwa ozugbo. Zụrụ Oxycodone Oxycontin 30mg online na Australia

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A nwalekwara ụzọ nchịkwa transdermal n'ime anụmanụ.

Taa, a na-ejikarị oxycodone eme ihe dị ka mbadamba ihe a na-achịkwa maka mgbu na-adịghị ala ala. A na-eji ngwọta ewepụtara ozugbo na mbadamba ihe maka nnukwu mgbu ma ọ bụ ihe mgbu. Parenteral oxycodone bụ ezigbo nhọrọ mgbe enweghị ike iji ọnụ na-enye opioids. Zụrụ Oxycodone Oxycontin 30mg n'ịntanetị na Australia.

Akụkọ | Oxycontin maka njikwa mgbu | Mushroomifi.

Opium nwere klas kemịkalụ abụọ nke alkaloids, phenantrenes na benzyl-isoquinolines. Otu n'ime phenantrene alkaloids, thebaine, dị na 0.2-0.8% nke opium sitere na Papaver somniferum yana na 90% nke ewepụtara na morphine na-enweghị Papaver bracteatum, dị oke nsi na enweghị ihe analgesic. Otú ọ dị, ọ bụ ihe mmalite dị mkpa nke ọtụtụ ngwaahịa mgbanwe, gụnyere oxycodone.

Oxycodone sitere na thebaine na 1916 wee weba ya n'ọrụ ahụike na Germany na 1917.
A na-eji ya na ugwu Europe tumadi maka nnukwu mgbu. Na Canada, Australia, na United States, a na-eji ya eme ihe karịsịa dị ka ọgwụ ngwakọta na acetaminophen, phenacetin, na caffeine maka mgbu na-adịghị ala ala. Na Finland, ejirila oxycodone mee ihe dị ka opioid parenteral bụ isi maka oke mgbu kemgbe 1960. Zụrụ Oxycodone Oxycontin 30mg n'ịntanetị na Australia.

Chemistry na Basic Pharmacology | OxyContin 30 mg mbadamba ntọhapụ ogologo oge | Mushroomifi.

Oxycodone (6-deoxy-7,8-dehydro-14-hydroxy-3-O-methyl-6-oxomorphine) molekul mejupụtara abụọ planar (A na B) na abụọ aliphatic mgbanaka (C na D). Ejikọtara otu dị mkpa maka omume analgesic nke phenantrenes na ọnọdụ C3, C6, na N.

Oxycodone nwere liposolubility yiri morphine, ma ha abụọ adịchaghị soluble lipid karịa fentanyl.

-opioid receptor. Zụrụ Oxycodone Oxycontin 30mg n'ịntanetị na Australia

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μ-opioid nnabata njikọ nke oxycodone, agbanyeghị, erughị nke morphine ma ọ bụ methadone.

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Oxymorphone, metabolite na-arụ ọrụ nke oxycodone, nwere njikọ μ-opioid nnabata nke dị elu nke ukwuu.

Atụnyere oxymorphone intramuscular na morphine na ndị ọrịa nwere mgbu na-adịghị ala ala n'ihi ọrịa kansa. Oxymorphone intramuscular gosipụtara na ọ nwere ike ugboro 8.7 ka morphine n'ihe gbasara mkpokọta analgesic mmetụta yana ugboro 13 dị ike n'ihe gbasara mmetụta kacha elu.

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Na ọmụmụ omume na oke, oxycodone e jirila ya tụnyere Morphine ma egosila mgbochi nke adịghị ike na nkenke dị na ọdụ ọdụ na ule ọkụ ọkụ mgbe nchịkwa intrathecal (ya) na intracerebroventricular (icv) gasịrị.
Mgbe nchịkwa usoro (subcutaneous ma ọ bụ intraperitoneal), oxycodone gosipụtara na ọ dị irè ugboro 2-4 karịa morphine. Zụrụ Oxycodone Oxycontin 30mg n'ịntanetị na Australia

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Nsonaazụ ndị a egosila na metabolites na-arụ ọrụ nke oxycodone (dịka ọmụmaatụ, oxymorphone) nwere ike ịdị mkpa na analgesia-mediated oxycodone. Nnyocha na-eji oke ojii Aguti nke na-ezughị ezu na enzyme CYP2D1, nke achọrọ O-demethylate oxycodone na oke, na ndị na-anabata opioid dị iche iche na-atụ aro na antinociceptive Mmetụta nke oxycodone nwere ike ịbụ κ-opioid receptor-mediated.

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