PREGABALIN (LYRICA) 300 MG X 56 CAPSULES

Ua ʻae ʻia ʻo Pregabalin mai ka United States Food and Drug Administration (FDA) ma 2004. Hoʻohana ʻia ia e mālama i ka ʻeha a me ka hopu ʻana. E kūʻai i ka lyrica pregabalin 300mg ma ka pūnaewele ma Australia

Nā hōʻailona apono ʻia e FDA[1][2][3][4]

• ʻO ka mālama ʻana i ka ʻeha neuropathic e pili ana me ka neuropathy peripheral diabetic
• Hoʻomaʻamaʻa ʻana i ka ʻeha neuropathic e pili ana i ka ʻeha o ke kuamoʻo
• ʻO ka ʻeha neuropathic mai ka postherpetic neuralgia
• Ka mālama ʻana i ka fibromyalgia
• ʻO ka lāʻau hoʻohui no ka hoʻomaka ʻana o ka hapa i nā pākeke me ka epilepsy. E kūʻai i ka lyrica pregabalin 300mg ma ka pūnaewele ma Australia

Hoʻohana ʻia ka inoa waho[5][6][7]

• ʻO ka hopohopo koʻikoʻi maʻamau
• ʻO nā hopohopo pili honua
• Bipolar kāna hana
• Kanikani'āʻula.
• Nā kūlana ʻeha mau
• Pruritus mau
• Mū kau mau
• ʻO ka maʻi hāmāʻole

Aia ka ʻokoʻa koʻikoʻi e pili ana i ka pono o ka pregabalin no nā maʻi psychiatric i helu ʻia ma luna. No laila, pono e makaʻala a nānā i nā mea maʻi no ka kūleʻa therapeutic i ka wā e mālama ai i nā maʻi me pregabalin. E kūʻai i ka lyrica pregabalin 300mg ma ka pūnaewele ma Australia

Ka hana hana

Ua like ka Pregabalin me ka inhibitory neurotransmitter gamma-aminobutyric acid (GABA). Ua hoʻololi ʻia e lilo i analog lipophilic e hoʻomaikaʻi i ka laha ʻana ma waena o ka pale koko-lolo. Eia naʻe, ʻaʻole pili pono ka pregabalin i nā mea hoʻokipa GABA-A a i ʻole GABA-B. Hoʻohui ʻia, ʻaʻole ia i metabolized i kahi agonist receptor GABA. I loko o nā hiʻohiʻona holoholona, ​​hoʻopaʻa ʻia ka pregabalin i nā kahawai calcium presynaptic voltage-gated ma ka subunit alpha-2-delta i loko o nā ʻiʻo o ka ʻōnaehana nerve waena. ʻO ka hoʻopaʻa ʻana o ka subunit alpha-2-delta e hoʻemi i ka depolarization-induced influx o ka calcium i loko o nā neurons a hoʻemi i ka hoʻokuʻu ʻana o nā neurotransmitters excitatory. Hiki i kēia hana ke helu i nā hopena anticonvulsant a me analgesic o pregabalin. ʻAʻohe hana i ʻike ʻia ʻo Pregabalin ma nā kahawai sodium, dopamine receptors, serotonin receptors, nā mea loaʻa opiate a ʻaʻole hoʻololi i ka hana cyclooxygenase.[8] E kūʻai i ka lyrica pregabalin 300mg ma ka pūnaewele ma Australia

hooponopono

Hāʻawi ʻia ʻo Pregabalin ma ka waha a loaʻa i loko o nā capsules a i ʻole nā ​​​​mea hoʻonā waha. Ma hope o ka lawelawe waha, hiki i ka pregabalin ke kiʻekiʻe o ka plasma plasma i loko o 1.5 mau hola a loaʻa i kahi kūlana paʻa i loko o 24 a 48 mau hola. ʻO ka absorption o pregabalin he kūʻokoʻa ia i ka nui. Ua hele koke ʻo Pregabalin i ka pale koko-lolo. ʻAʻole hiki i nā kānaka ke hoʻololi nui i ka pregabalin. ʻO kona hoʻopau ʻia ʻana ma ke ʻano he lāʻau i hoʻololi ʻole ʻia (ma lalo o 2% metabolized) e ka renal excretion. I nā mea maʻi me ka hana renal maʻamau, ʻo ka mean elimination half-life he 6.3 mau hola. Ua aʻo nā mea noiʻi i ka pregabalin ma nā dosages a hiki i 600 mg i kēlā me kēia lā. Eia naʻe, ʻaʻole i loaʻa iā lākou ka 600 mg i kēlā me kēia lā e hāʻawi i ka pōmaikaʻi hou aʻe a ʻaʻole i ʻae ʻia ma muli o nā hopena ʻaoʻao. E kūʻai i ka lyrica pregabalin 300mg ma ka pūnaewele ma Australia

Kū'ē

• Hoʻopaʻa ʻia ʻo Pregabalin i nā poʻe maʻi i ʻike i ka hypersensitivity i ka pregabalin. Ua loaʻa nā hopena hypersensitivity i nā mea maʻi e loaʻa ana i ka pregabalin, me ka angioedema.[19]
• ʻAʻohe haʻawina kūpono me pregabalin i nā wahine hāpai. Hiki i ka Pregabalin ke hōʻeha i ka pēpē. E aʻo i ka poʻe maʻi he pilikia paha i ka fetus.[20]
• Ua ʻike ʻia ʻo Pregabalin i ka waiū o nā wahine lactating; no laila, ʻaʻole pono ka hānai ʻana, a ʻoi aku ka maikaʻi o kahi mea hana ʻē aʻe.[15] E kūʻai i ka lyrica pregabalin 300mg ma ka pūnaewele ma Australia