Thenga i-Ketamine Powder 99% ubunyulu kwi-Intanethi | Inkcazo | I-MushroomiFi

Name: I-Ketamine Powder 99% yococeko-Thenga iMushroom yomlingo kwi-Intanethi |MushroomiFi
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I-Ketamine yaziswa ngokurhweba ngo-1970 kunye nenkcazo yomenzi "njengeyeza elikhawulezayo, elingena-barbiturate jikelele" kunye nesiphakamiso sokuba inokuba luncedo kwiinkqubo ezimfutshane. Ngoncedo lweempawu zayo zakudala ezikhethekileyo ze-pharmacological kunye neempawu zeklinikhi ezisanda kufunyanwa, i-ketamine iye yasinda kwimimoya eqinile yexesha, kwaye okwangoku ineendlela ezahlukeneyo zeklinikhi. Isanda kufunyanwa i-neuroprotective, anti-inflammatory and antitumor effects, kunye nokufunyaniswa koncedo lwedosi ephantsi yeerejimeni ze-ketamine zincede ekwandiseni iprofayile yesicelo seklinikhi ye-ketamine. Inqaku langoku lizama ukuphonononga izicelo ezikhoyo eziluncedo ze-ketamine kwi-anesthesia, intlungu kunye nokunyamekela okubalulekileyo. Isekelwe kubungqina benzululwazi obuqokelelwe kwiincwadi zezifundo, iijenali, kunye nogcino-lwazi lwe-elektroniki. Thenga i-ketamine powder hydrochloride kwi-intanethi e-Australia

Internet: I-anesthesia, izicelo zeklinikhi, ukhathalelo olubalulekileyo, ichiza, i-ketamine, izifo zabantwana, iintlungu, ukhathalelo lokuthomalalisa, i-perioperative analgesia

Yiya e:

Ketamine Hcl ababoneleli kunye nabavelisi | INTSHAYELELO | I-MushroomiFi

I-Ketamine isetyenziswa kwikliniki ukususela ngo-1970.1] Yinto ekhethekileyo ye-intravenous (IV) i-anesthetic evelisa uluhlu olubanzi lweempembelelo ze-pharmacological ezibandakanya ukutshatyalaliswa, i-catalepsy, i-analgesia ye-somatic, i-bronchodilation, kunye nokuvuselela inkqubo ye-nervous system.2] Ubukho bamachiza amatsha, ukuvela kokuphazamiseka kokuvela kweketamine, ibala layo “njengeyeza lezilwanyana” kunye nokufumana ukuthandwa njengechiza elinamandla okusebenzisa kakubi zizinto, ezinokukutyhafisa ukusetyenziswa kwayo ngoogqirha banamhlanje abaneesthesiologists.[3,4] Nangona kunjalo, i-ketamine ngenxa yeempawu zayo ezizodwa kunye neempawu zeklinikhi ezisanda kufunyanwa ziye zahlala ixesha elide.3,4,5,6,7] Inoluhlu olubanzi lwezicelo zeklinikhi nanamhlanje. Uninzi lwee-anesthesiologists zanamhlanje zifumana uqeqesho oluncinci nge-ketamine.8] Abazi malunga nezicelo zeklinikhi ezibanzi ze-ketamine. Ukugcina oku engqondweni, uphando olucokisekileyo loncwadi lwenziwa ngePubMed kunye neCochrane yolwazi lwe-elektroniki. Iincwadi ezahlukeneyo zezifundo ezisemgangathweni kunye neejenali ze-anesthesia ziye zajongwa. Ngokusekelwe kule nto, izibonakaliso zangoku ze-ketamine kwi-anesthesia, intlungu kunye nokunyamekela okubalulekileyo kuxoxwa ngayo kweli nqaku lokuphonononga. Thenga i-ketamine powder hydrochloride kwi-intanethi e-Australia

Yiya e:

I-PHARMACOLOGY YE-KETAMINE NGOKUFUTSHANE

Ikhemistri esisiseko

I-Ketamine yinto ephuma emanzini e-soluble phencyclidine. I ketamine Imolekyuli iqulathe iathom yekhabhoni eneasymmetric ene-enantiomers ezimbini: I-isomer ye-S(+) kunye ne-R(-) isoma.9]

Pharmacokinetics

I-Ketamine i-soluble kakhulu ye-lipid kwaye iyancipha ngokukhawuleza kwaye Ukunikezelwa ngokutsha kwizicubu ze-peripheral. I-metabolized ngokubanzi kwisibindi nge-N-demethylation kunye ne-ring hydroxylation pathways.1,10] I-Norketamine iyona imetabolite ephambili kwaye isinye kwisithathu ukuya kwisinye kwisihlanu esinamandla njenge-ketamine njenge-anesthetic. I-ketamine ikhutshelwa emchameni nakwilindle njenge-norketamine nanjenge-hydroxylated derivatives. Inesiphumo esongezelekayo. Ukuchasa ngokuthe ngcembe kwakhela kulawulo oluphindaphindiweyo.10] Thenga i-ketamine powder hydrochloride kwi-intanethi e-Australia

Pharmacodynamics

I-Ketamine ivuselela inkqubo ye-cardiovascular ebangela ukunyuka kwesantya sentliziyo, uxinzelelo lwegazi kunye nokwanda kwemveliso yentliziyo, idibene ngokuyinhloko ngenkqubo ye-nervous enovelwano.11] Ineempembelelo ezincinci kwi-central respiratory drive kwaye ivelise ukuphumla kwendlela yomoya ngokusebenza kwii-receptors ezahlukeneyo kunye nee-cascade ezivuthayo kunye nezihlunu ezigudileyo ze-bronchial.1,9] Yandisa amathe kunye nethoni yezihlunu.11] Ine-cataleptic, i-amnestic, i-analgesic enzulu, kunye neentshukumo ezixhomekeke kwithamo lokuthomalalisa iintlungu.10,11] I-cataleptic state yimeko ye-akinetic kunye nokulahlekelwa kwe-orthostatic reflexes, kodwa ngaphandle kokuphazamiseka kwengqondo.10,12] I-dissociative state eveliswa yi-ketamine iyingqayizivele apho isigulane sibonakala siphapheme, kodwa sikhutshwe kwindawo ejikelezileyo ngamehlo ahlala evulekile.11] Thenga i-ketamine powder hydrochloride kwi-intanethi e-Australia