E kūʻai i ka pauka Ketamine 99% maʻemaʻe ma ka pūnaewele | Puka | MushroomiFi

Name: ʻO ka pauka Ketamine 99% maʻemaʻe - kūʻai aku i ka Mushroom Magic Online | MushroomiFi
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Ua hoʻokomo ʻia ʻo Ketamine ma ke kālepa i ka makahiki 1970 me ka wehewehe ʻana o ka mea hana ma ke ʻano he "wikiwiki, nonbarbiturate general anesthetic" a me kahi manaʻo e pono ia no nā kaʻina hana pōkole. Me ke kōkua o kāna mau waiwai pharmacological kūʻokoʻa kahiko a me nā waiwai lapaʻau maikaʻi hou i ʻike ʻia, ua ola ketamine i nā makani ikaika o ka manawa, a i kēia manawa he nui nā ʻano noiʻi lapaʻau. Ua ʻike hou ʻia nā hopena neuroprotective, antiinflammatory a me antitumor, a ʻo ka ʻike ʻana i ka pono o nā regimens haʻahaʻa ketamine ua kōkua i ka hoʻonui ʻana i ka ʻike noiʻi noiʻi o ketamine. Ke hoʻāʻo nei ka ʻatikala o kēia manawa e loiloi i nā noi kūpono o ketamine i kēia manawa i ka anesthesia, ʻeha a me ka mālama koʻikoʻi. Hoʻokumu ʻia ia ma nā hōʻike ʻepekema i hōʻiliʻili ʻia mai nā puke, nā puke pai, a me nā ʻikepili uila. E kūʻai i ka pauka ketamine hydrochloride ma ka pūnaewele ma Australia

Keywords: Anesthesia, nā noi lapaʻau, mālama koʻikoʻi, lāʻau lapaʻau, ketamine, pediatrics, ʻeha, mālama palliative, analgesia perioperative

E hele:

Ketamine Hcl Nā mea kūʻai a me nā mea hana | OLELO HOOLAHA | MushroomiFi

Hoʻohana ʻia ka Ketamine mai ka makahiki 1970.[1] He mea hoʻomaʻemaʻe kūʻokoʻa i loko o ke koko (IV) e hoʻopuka ana i kahi ākea ākea o nā hopena pharmacological e pili ana i ka sedation, catalepsy, somatic analgesia, bronchodilation, a me ka hoʻoulu ʻana i ka ʻōnaehana nerve aloha.[2] ʻO ka loaʻa ʻana o nā lāʻau lapaʻau hou, ʻo ka hoʻopilikia ʻana i nā hopena o ka ketamine, kona stigma ma ke ʻano he "lāʻau lapaʻau vet" a me ka loaʻa ʻana o ka kaulana ma ke ʻano he lāʻau lapaʻau me ka hiki ke hoʻomāinoino ʻia nā kumu, e hoʻohaʻahaʻa i ka hoʻohana ʻana e nā anesthesiologists i kēia lā.[3,4] Eia naʻe, ua kū ka ketamine ma muli o kāna mau waiwai kūʻokoʻa a me nā mea lapaʻau hou i ʻike ʻia.[3,4,5,6,7] Loaʻa iā ia ka laulā o nā noi lapaʻau a hiki i kēia lā. Loaʻa ka hapa nui o ka poʻe anesthesiologists i ka liʻiliʻi o ka hoʻomaʻamaʻa ʻana me ka ketamine.[8] ʻAʻole lākou i ʻike i ka hoʻohana nui ʻana o ke ketamine. Ma ka hoʻomanaʻo ʻana i kēia, ua mālama ʻia kahi hulina palapala ma o PubMed a me Cochrane ʻikepili uila. Ua kūkākūkā ʻia nā puke aʻo maʻamau a me nā puke moʻolelo o ka anesthesia. Ma muli o kēia, ua kūkākūkā ʻia nā hōʻailona o kēia manawa o ka ketamine i ka anesthesia, ka ʻeha a me ka mālama koʻikoʻi ma kēia ʻatikala loiloi. E kūʻai i ka pauka ketamine hydrochloride ma ka pūnaewele ma Australia

E hele:

PHARMACOLOGY O KETAMINE I KA PILI

Kemika kumu

ʻO ka Ketamine he wai hoʻoheheʻe phencyclidine. ʻO ka ketamine Loaʻa ka molekala i kahi ʻātoma kalapona asymmetric me ʻelua enantiomers: ʻO ka isomer S(+) a me ka isomer R(−).[9]

ʻO Pharmacokinetics

ʻO ketamine ka lipid soluble nui a ke hele wikiwiki nei a lāhoʻi hou i nā ʻiʻo peripheral. Hoʻopili ʻia ʻo ia i loko o ke akepaʻa e N-demethylation a me nā ala hydroxylation apo.[1,10] ʻO Norketamine ka metabolite nui a ʻo ka hapakolu a i ka hapalima ka ikaika e like me ka ketamine ma ke ʻano he anesthetic. Hoʻokuʻu ʻia ʻo Ketamine i ka mimi a me nā feces e like me ka norketamine a me nā derivatives hydroxylated. He hopena kumulative. Hoʻonui ʻia ke kūʻē mālie ʻana i ka hoʻoponopono ʻana.[10] E kūʻai i ka pauda ketamine hydrochloride ma ka pūnaewele ma Australia

ʻO Pharmacodynamics

Hoʻoulu ʻo Ketamine i ka ʻōnaehana cardiovascular ma muli o ka piʻi ʻana o ka puʻuwai puʻuwai, ke kahe koko a me ka piʻi ʻana o ka puʻuwai puʻuwai, i hoʻopili ʻia ma o ka ʻōnaehana sympathetic nerve.[11] He liʻiliʻi kona hopena ma ka hoʻokele hanu waena a hoʻopuka i ka hoʻomaha hoʻomaha ea ma o ka hana ʻana i nā mea hoʻokipa like ʻole a me nā cascade inflammatory a me nā ʻiʻo maʻemaʻe bronchial.[1,9] Hoʻonui ia i ka salivation a me ke kani o ka ʻiʻo.[11] Loaʻa iā ia ka cataleptic, amnestic, hohonu analgesic, a me ka dose dependent anesthetic hana.[10,11] ʻO ka mokuʻāina cataleptic kahi mokuʻāina akinetic me ka nalo ʻana o nā reflexes orthostatic, akā me ka ʻole o ka hōʻino ʻana o ka ʻike.[10,12] ʻO ka mokuʻāina dissociative i hana ʻia e ka ketamine he mea kū hoʻokahi kahi i ʻike ʻia ai ka mea maʻi e ala ana, akā ua kaʻawale ʻia mai nā wahi a puni me ka wehe ʻana o nā maka.[11] E kūʻai i ka pauda ketamine hydrochloride ma ka pūnaewele ma Australia