PREGABALIN (LYRICA) 300 MG X 56 CAPSULES

Pregabalin ya sami izini daga Hukumar Kula da Abinci da Magunguna ta Amurka (FDA) a cikin 2004. Ana amfani da shi don magance ciwo da tashin hankali. Sayi lyrica pregabalin 300mg akan layi a Ostiraliya

Alamun da aka yarda da FDA[1][2][3][4]

• Maganin ciwon neuropathic da ke hade da ciwon sukari na gefe neuropathy
• Maganin ciwon neuropathic da ke hade da raunin kashin baya
• Ciwon Neuropathic wanda ya samo asali daga neuralgia postherpetic
• Maganin fibromyalgia
• Maganin haɗin gwiwa don ɓarna-ɓangarorin farko a cikin manya masu ciwon farfaɗiya. Sayi lyrica pregabalin 300mg akan layi a Ostiraliya

Kashe-lakabin Amfani[5][6][7]

• Rashin damuwa gabaɗaya
• Rashin damuwa na zamantakewa
• Bipolar cuta
• rashin barci
• Yanayin zafi na yau da kullun
• Pruritus na kullum
• Tari mai tsawo
• Ciwon kafa mara hutawa

Akwai babban rashin jituwa game da tasirin pregabalin don cututtukan hauka da aka jera a sama. Sabili da haka, masu rubutawa ya kamata su yi hankali kuma su saka idanu marasa lafiya don samun nasarar warkewa lokacin da ake kula da marasa lafiya tare da pregabalin. Sayi lyrica pregabalin 300mg akan layi a Ostiraliya

Kayan aikin

Pregabalin yana da tsari kama da inhibitory neurotransmitter gamma-aminobutyric acid (GABA). An canza shi ya zama analog na lipophilic don haɓaka yaduwa a cikin shingen kwakwalwar jini. Koyaya, pregabalin baya ɗaure kai tsaye ga masu karɓar GABA-A ko GABA-B. Bugu da ƙari, ba a daidaita shi zuwa agonist mai karɓar GABA. A cikin ƙirar dabba, pregabalin yana ɗaure zuwa tashoshi na presynaptic voltaji-gated calcium a sashin alpha-2-delta a cikin kyallen jikin tsarin juyayi na tsakiya. Daure na alpha-2-delta subunit yana rage kwararar alli da ke haifar da depolarization zuwa neurons kuma yana rage sakin masu jiwuwa masu motsa rai. Wannan aikin na iya yin lissafin sakamako na anticonvulsant da analgesic na pregabalin. Pregabalin ba shi da sanannun aiki a tashoshin sodium, masu karɓar dopamine, serotonin rabe, masu karɓa na opiate kuma baya canza ayyukan cyclooxygenase.[8] Sayi lyrica pregabalin 300mg akan layi a Ostiraliya

Administration

Ana gudanar da Pregabalin ta baki kuma ana samunsa a cikin capsules ko mafita na baka. Bayan gudanar da baki, pregabalin ya kai matsakaicin adadin plasma a cikin sa'o'i 1.5 kuma ya cimma daidaito tsakanin sa'o'i 24 zuwa 48. Shanyewar pregabalin ya kasance mai zaman kansa daga kashi. Pregabalin a hankali ya ketare shingen kwakwalwar jini. Mutane ba za su iya sarrafa pregabalin sosai ba. Kawar da ita shine da farko azaman magani mara canzawa (kasa da 2% metabolized) ta hanyar fitar da koda. A cikin marasa lafiya da aikin koda na al'ada, ma'anar kawar da rabin rayuwa shine sa'o'i 6.3. Masu bincike sun yi nazarin pregabalin a allurai har zuwa 600 MG kowace rana. Duk da haka, ba su sami 600 MG kowace rana don samar da ƙarin fa'ida mai mahimmanci ba kuma ba a yarda da su sosai ba saboda sakamako masu illa. Sayi lyrica pregabalin 300mg akan layi a Ostiraliya

contraindications

• Pregabalin an hana shi a cikin marasa lafiya waɗanda ke da sanannen hauhawar jini ga pregabalin. Haɓaka haɓakawa sun faru a cikin marasa lafiya da ke karɓar pregabalin, gami da angioedema.[19]
• Babu isasshen karatu tare da pregabalin a cikin mata masu juna biyu. Pregabalin na iya haifar da lahani ga tayin. Shawara marassa lafiya akwai yuwuwar haɗari ga tayin.[20]
• An gano Pregabalin a cikin madarar mata masu shayarwa; don haka, shayarwa ba ta da kyau, kuma an fi son madadin wakili.[15] Sayi lyrica pregabalin 300mg akan layi a Ostiraliya